OrthoSon: developing a safer, cost-effective treatment to restore spine function and alleviate symptoms, for patients living with persistent, discogenic low back pain.
Patented Sonosensitive particles are injected into a degenerated intervertebral disc and activated with external ultrasound to perform a controlled nucleotomy, all with full real-time ultrasound imaging. Our hydrogel is then injected, forming in-situ to create a prosthetic nucleus pulposus with a physiological form factor for sustainable restoration.
The entire procedure is designed around a single 0.5mm puncture in the annulus fibrosus and to be performed on a day-case basis. Our patented Passive Acoustic MappingTM procedure will image the nucleotomy in real time for safety and control.
Patented Sonosensitive particles are injected into a degenerated intervertebral disc and activated with external ultrasound to perform a controlled nucleotomy, all with full real-time ultrasound imaging. Our hydrogel is then injected, forming in-situ to create a prosthetic nucleus pulposus with a physiological form factor for sustainable restoration.
The entire procedure is designed around a single 0.5mm puncture in the annulus fibrosus and to be performed on a day-case basis. Our patented Passive Acoustic MappingTM procedure will image the nucleotomy in real time for safety and control.
Location: United Kingdom, England, Oxford
Employees: 11-50
Founded date: 2016
Investors 4
| Date | Name | Website |
| - | Winton Ven... | winton.com |
| - | Oxford Inv... | oxfordinve... |
| - | Perivoli I... | perivoliin... |
| 29.05.2022 | Big Pi | bigpi.vc |
Mentions in press and media 4
| Date | Title | Description |
| 04.04.2026 | Alcatraz Secures $50 Million to Revolutionize Physical Security with AI Biometrics | Alcatraz, a pioneering firm in AI-powered physical access control, recently secured $50 million in Series B funding. This significant investment fuels its expansion, targeting critical infrastructure worldwide. The company’s facial authenti... |
| 01.04.2026 | BlackPeak Capital Backs Biometric Security Firm Alcatraz in a Series B Funding Round | Bulgaria, USA ~ Company: Bulgarian BlackPeak Capital has announced a new investment in Bulgarian-founded Alcatraz, a company specializing in facial biometric authentication for physical access control, as part of a $35 (€29.77) million Seri... |
| 11.05.2022 | Big Pi Ventures invests in OrthoSon’s €10.4M Series A to help treat lower back pain | Greece, United Kingdom ~ • Greek technology venture capital firm Big Pi Ventures participated in OrthoSon’s €10.4M (£8.9M) recent Series A, next to international investors such as Yonghua Capital. • OrthoSon, a startup based in Oxford, UK, ... |
| 26.03.2019 | “Our technology is lightyears ahead”: Aussie micro-influencer platform Tribe raises $10.5 million to launch in the Big Apple | Tribe chief executive Anthony Svirskis and founder Jules Lund. Source: Supplied. Aussie micro-influencer startup Tribe has raised $10.5 million in funding, to fuel its expansion into the US market. Founded in 2015 by TV and radio host Jules... |